Journal article
Concurrent dual allergen exposure and its effects on airway hyperresponsiveness, inflammation and remodeling in mice
Abstract
Experimental mouse models of asthma have broadened our understanding of the mechanisms behind allergen-induced asthma. Typically, mouse models of allergic asthma explore responses to a single allergen; however, patients with asthma are frequently exposed to, and tend to be allergic to, more than one allergen. The aim of the current study was to develop a new and more relevant mouse model of asthma by measuring the functional, inflammatory and …
Authors
DiGiovanni FA; Ellis R; Wattie J; Hirota JA; Southam DS; Inman MD
Journal
Disease Models & Mechanisms, Vol. 2, No. 5-6, pp. 275–282
Publisher
The Company of Biologists
Publication Date
April 30, 2009
DOI
10.1242/dmm.001859
ISSN
1754-8403