Journal article
Mutagen screening with bacteria: Niridazole and nitrofurans
Abstract
The mutagenic activity of nitrofuran derivatives and of niridazole is easily demonstrated by spot tests using E. coli WP2 and its uvrA derivative but not by spot tests using the S. typhimurium strains developed by Ames. Quantitative tests show that S. typhimurium TA 1538(but not TA 1535, -36 or -37) is weakly induced to revert by niridazole. However, the maximum yield of revertants is well below that obtained with E. coli WP2 uvrA. None of the …
Authors
McCalla DR; Voutsinos D; Olive PL
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 31, No. 1, pp. 31–37
Publisher
Elsevier
Publication Date
February 1975
DOI
10.1016/0165-1161(75)90060-6
ISSN
0027-5107