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Decreasing antibiotic use, the gut microbiota, and...
Journal article

Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies

Abstract

BACKGROUND: Childhood asthma incidence is decreasing in some parts of Europe and North America. Antibiotic use in infancy has been associated with increased asthma risk. In the present study, we tested the hypothesis that decreases in asthma incidence are linked to reduced antibiotic prescribing and mediated by changes in the gut bacterial community. METHODS: This study comprised population-based and prospective cohort analyses. At the …

Authors

Patrick DM; Sbihi H; Dai DLY; Al Mamun A; Rasali D; Rose C; Marra F; Boutin RCT; Petersen C; Stiemsma LT

Journal

The Lancet Respiratory Medicine, Vol. 8, No. 11, pp. 1094–1105

Publisher

Elsevier

Publication Date

November 2020

DOI

10.1016/s2213-2600(20)30052-7

ISSN

2213-2600