Journal article
Impaired alternative macrophage differentiation of peripheral blood mononuclear cells from obese subjects
Abstract
Visceral obesity is a chronic, low-grade inflammatory disease that predisposes people to the metabolic syndrome, type 2 diabetes and its cardiovascular complications. Adipose tissue is not a passive storehouse for fat, but an endocrine organ synthesizing and releasing a variety of bioactive molecules, some of which are produced by infiltrated immune-inflammatory cells including macrophages. Two different subpopulations of macrophages have been …
Authors
Bories G; Caiazzo R; Derudas B; Copin C; Raverdy V; Pigeyre M; Pattou F; Staels B; Chinetti-Gbaguidi G
Journal
Diabetes and Vascular Disease Research, Vol. 9, No. 3, pp. 189–195
Publisher
SAGE Publications
Publication Date
July 2012
DOI
10.1177/1479164111430242
ISSN
1479-1641