Journal article
A longitudinal characterization of the Non-Cystic Fibrosis Bronchiectasis airway microbiome
Abstract
A diverse microbiota exists within the airways of individuals with non-cystic fibrosis bronchiectasis (nCFB). How the lung microbiome evolves over time, and whether changes within the microbiome correlate with future disease progression is not yet known. We assessed the microbial community structure of 133 serial sputa and subsequent disease course of 29 nCFB patients collected over a span of 4–16 years using 16S rRNA paired-end sequencing. …
Authors
Woo TE; Lim R; Heirali AA; Acosta N; Rabin HR; Mody CH; Somayaji R; Surette MG; Sibley CD; Storey DG
Journal
Scientific Reports, Vol. 9, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41598-019-42862-y
ISSN
2045-2322