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Ventromedial hypothalamic lesions eliminate...
Journal article

Ventromedial hypothalamic lesions eliminate gastric acid secretion elicited by anticipated eating

Abstract

Electrolytic lesions of the ventromedial hypothalamus (VMH) produce an obesity syndrome characterized, in part, by excessive food intake and adiposity. Several hypotheses suggest that VMH lesion-induced hyperphagia results from elevated parasympathetic tone on the viscera expressed via the vagus nerves. To evaluate this possibility, vagally-mediated gastric acid secretion was measured in control and VMH-lesion rats. Initially, Pavlovian …

Authors

Weingarten HP; Parkinson W

Journal

Appetite, Vol. 10, No. 3, pp. 205–219

Publisher

Elsevier

Publication Date

June 1988

DOI

10.1016/0195-6663(88)90013-x

ISSN

0195-6663