Journal article
High-Throughput Screening for Inhibitors of Wall Teichoic Acid Biosynthesis in Staphylococcus aureus
Abstract
The world is heading toward a dangerous post-antibiotic era where antibiotics fail to treat infections. Staphylococcus aureus is the leading cause of healthcare-associated infections worldwide, and an ever-increasing percentage of them are methicillin-resistant (MRSA). New strategies are urgently needed to combat this pathogen. Wall teichoic acids (WTA) in S. aureus are polyribitol phosphate polymers that play important roles in virulence and …
Authors
El-Halfawy OM; Brown ED
Journal
Methods in Molecular Biology, Vol. 1954, , pp. 297–308
Publisher
Springer Nature
Publication Date
2019
DOI
10.1007/978-1-4939-9154-9_23
ISSN
1064-3745