HLA typing in actinic prurigo Academic Article uri icon

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abstract

  • Thirty-two actinic prurigo patients of Cree ancestry underwent human lymphocyte antigen (HLA) typing and were compared with 32 control subjects of Cree ancestry. We found a significantly increased frequency of HLA-A24 and Cw4 antigens and a significant decrease in the frequency of the A3 antigen in actinic prurigo patients. These HLA associations may be helpful in determining whether actinic prurigo is a distinct disease or a variant of polymorphous light eruption.

authors

  • Sheridan, David P
  • Lane, Peter R
  • Irvine, James
  • Martel, Marie J
  • Hogan, Daniel J

publication date

  • June 1990