selected scholarly activity
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conferences
- Intracellular proteases and sarcomere disassembly in neonatal cardiomyocytes. The FASEB Journal. 2013
- Role of MMP-2 activation in oncostatin-M induced cardiomyocyte dedifferentiation. The FASEB Journal. 2013
- LONG-TERM TREATMENT WITH RECOMBINANT-HUMAN-ERYTHROPOIETIN (RHUEPO) IN THALASSEMIA - REDUCTION IN REQUIREMENT FOR TRANSFUSION AND CHELATION-THERAPY. Blood. A258-A258. 1994
- RED-CELL CREATINE AND FREE ERYTHROCYTE PROTOPORPHYRIN IN PREMATURE AND FULL-TERM INFANTS DURING THE 1ST 6 MONTHS OF LIFE. Pediatric Research. A392-A392. 1986
- ANTIIDIOTYPIC ANTIBODIES AND SUPPRESSOR CELLS (SC) IN PATIENTS RECEIVING DONOR SPECIFIC BLOOD-TRANSFUSIONS (DST). Clinical and Investigative Medicine. A165-A165. 1986
- AN APPROACH TO DETERMINE OPTIMAL HB STANDARDS FOR BLOOD-DONORS. Transfusion. 418-418. 1984
- INCIDENCE AND CAUSE OF HYPOCHROMIC BLOOD PICTURE IN HOSPITAL POPULATION. Clinical Research. A692-A692. 1977
- SERUM FERRITIN VERSUS SERUM IRON AND IRON-BINDING IN EVALUATION OF IRON-DEFICIENCY ANEMIA. Clinical Biochemistry. P8-P8. 1977
- 4 NONSTEROIDAL ANTIINFLAMMATORY DRUGS AS INHIBITORS OF PLATELET AND GASTRIC MUCOSAL PROSTAGLANDIN SYNTHESIS. Clinical Research. A669-A669. 1976
- DIAGNOSIS OF INTRAVASCULAR HEMOLYSIS BY STARCH-GEL ELECTROPHORESIS. Clinical Research. A670-A670. 1976
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journal articles
- RYBP Is a K63-Ubiquitin-Chain-Binding Protein that Inhibits Homologous Recombination Repair. Cell Reports. 22:383-395. 2018
- Matrix metalloproteinase-2 in oncostatin M-induced sarcomere degeneration in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 311:H183-H189. 2016
- Dynamic Alterations to α-Actinin Accompanying Sarcomere Disassembly and Reassembly during Cardiomyocyte Mitosis. PLoS ONE. 10:e0129176-e0129176. 2015
- Hydrogen peroxide-induced necrotic cell death in cardiomyocytes is independent of matrix metalloproteinase-2. Toxicology in Vitro. 27:1686-1692. 2013
- Mechanisms of cytosolic targeting of matrix metalloproteinase‐2. Journal of Cellular Physiology. 227:3397-3404. 2012
- Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity. Biochemical and Biophysical Research Communications. 423:1-5. 2012
- Cardiac Sarcomeric Proteins: Novel Intracellular Targets of Matrix Metalloproteinase-2 in Heart Disease. Trends in Cardiovascular Medicine. 21:112-118. 2011
- Titin is a Target of Matrix Metalloproteinase-2. Circulation. 122:2039-2047. 2010
- Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix. Cardiovascular Research (CVR). 85:413-423. 2010
- Activation of MMP-2 as a key event in oxidative stress injury to the heart. Frontiers in Bioscience - Landmark. Volume:699-699. 2009
- PPARα: essential component to prevent myocardial oxidative stress?. American Journal of Physiology. Heart and Circulatory Physiology. 293:H11-H12. 2007
- An Algorithm to Aid in the Investigation of Thalassemia Trait in Multicultural Populations. Archives of Pathology and Laboratory Medicine. 124:1320-1323. 2000
- Vascular volumes and hematology in male and female runners and cyclists. European Journal of Applied Physiology. 79:244-250. 1999
- The Effect of Carbon Tetrachloride on the Detection of Hemoglobin H Using Various Commercially Available Electrophoresis Products. American Journal of Clinical Pathology. 109:651.2-652. 1998
- Detection of α2- and α1- Globin Gene Variants by a Modified Cycle Sequencing Method. Hemoglobin. 22:373-376. 1998
- Proficiency Testing of Hemoglobinopathy Techniques in Ontario Laboratories. American Journal of Clinical Pathology. 107:567-575. 1997
- Recognizing and investigating iron-deficiency anemia in hospitalized elderly people.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 155:691-696. 1996
- The Evaluation of Various Mathematical RBC Indices and Their Efficacy in Discriminating Between Thalassemic and Non-Thalassemic Microcytosis. American Journal of Clinical Pathology. 106:201-205. 1996
- Acute hemolytic anemia precipitated by myocardial infarction and pericardial tamponade in G6PD deficiency. American Journal of Hematology. 51:174-175. 1996
- Failure of prolonged exercise training to increase red cell mass in humans. American Journal of Physiology. 270:H121-H126. 1996
- A prospective study to determine the frequency and clinical significance of alloimmunization post‐transfusion. British Journal of Haematology. 91:1000-1005. 1995
- Identifican of A New High Oxygen Affinity Hemoglobin Variant: Hb Aurora [β139(H17)Asn→Tyr]. Hemoglobin. 19:335-341. 1995
- Hemoglobinopathies: three illustrative case studies. Clinical and Investigative Medicine. 17:461-465. 1994
- Myelodysplastic syndrome with prolonged reticulocyte survival mimicking hemolytic disease. American Journal of Clinical Pathology. 101:149-153. 1994
- PHYSICIANS PERCEPTIONS OF LABORATORY COSTS IN THE INTENSIVE-CARE UNIT. Clinical and Investigative Medicine. 15:476-481. 1992
- The clinical significance of hemoglobinopathies in the Hamilton region: a twenty-year review. Clinical and Investigative Medicine. 15:401-405. 1992
- A prospective study to determine the safety of omitting the antiglobulin crossmatch from pretransfusion testing. British Journal of Haematology. 81:579-584. 1992
- Laboratory diagnosis of iron-deficiency Anemia: An overview. Journal of General Internal Medicine. 7:423-423. 1992
- Effect of n-3 fatty acids from fish oil on hemostasis, blood pressure, and lipid profile of dialysis patients. Journal of the American Society of Nephrology. 2:1634-1639. 1992
- Laboratory diagnosis of iron-deficiency anemia: an overview. Journal of General Internal Medicine. 7:145-153. 1992
- The protective effect of vitamin E on the hemolysis associated with dapsone treatment in patients with dermatitis herpetiformis. Archives of Dermatology. 128:210-213. 1992
- Oral iron absorption in hemodialysis patients treated with erythropoietin.. Clinical and Investigative Medicine. 14:271-276. 1991
- Response of red cell and plasma volume to prolonged training in humans. Journal of applied physiology. 70:1810-1815. 1991
- Iron deficiency anemia in the elderly: the diagnostic process.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 144:435-440. 1991
- Iron deficiency in the elderly: The diagnostic process. Annals of Internal Medicine. 115:54. 1991
- Bioavailability of Iron in Hemodialysis Patients Treated With Erythropoietin: Evidence for the Inhibitory Role of Aluminum. American Journal of Kidney Diseases. 16:447-451. 1990
- The effect of alpha-hemoglobin gene deletions on the red blood cells' mean cell volume and hemoglobin levels.. Translational Research. 116:573-574. 1990
- Diagnosis of iron-deficiency anemia in the elderly. American Journal of Medicine. 88:205-209. 1990
- Recurrent acute splenic sequestration crisis due to interacting genetic defects: hemoglobin SC disease and hereditary spherocytosis. Blood. 75:266-270. 1990
- Positional effect of cis/trans alpha globin gene deletions on the formation of “H” bodies. American Journal of Hematology. 31:242-247. 1989
- A prospective study evaluating the lowering of hemoglobin standards for blood donors. Transfusion. 29:268-272. 1989
- The Interaction of Anti 3. 7 Type Quadruplicated α-Globin Genes and Heterozygous β-Thalassemia. Hemoglobin. 13:125-135. 1989
- Hypergammaglobulinemia can be associated with a positive direct antiglobulin test, a nonreactive eluate, and no evidence of hemolysis. Transfusion. 28:29-33. 1988
- Some Rare Hemoglobin Variants with Altered Oxygen Affinities; Hb Linkoping [β36(C2)Pro→Thr], Hb Caribbean [β91(F7)Leu→Ar6], and Hb Sunnybrook [β 36(C2)Pro→Arg]. Hemoglobin. 12:137-148. 1988
- Developmental changes in red cell creatine and free erythrocyte protoporphyrin in healthy premature infants during the first six months of life. Journal of Pediatrics. 111:745-747. 1987
- Anti-idiotypic antibodies and suppressor cells in patients receiving pretransplant donor-specific blood transfusions.. Transplantation Proceedings. 19:3399-3401. 1987
- Developmental changes in red cell creatine and free erythrocyte protoporphyrin in healthy full-term infants during the first 6 months of life. Journal of Pediatrics. 108:732-734. 1986
- Gold induced aplastic anemia.. Journal of Rheumatology. 12:1011-1012. 1985
- Polyclonal B cell hyperplasia associated with Epstein-Barr virus causing acute renal allograft failure.. Clinical Nephrology. 24:151-154. 1985
- An approach to determine objectively minimum hemoglobin standards for blood donors. Transfusion. 25:286-288. 1985
- Compound Heterozygosity for two Genotypes of α-Thalassemia-2 : Hematological, Biosynthetic and DNA Studies. Hemoglobin. 9:111-126. 1985
- The clinical significance of hemoglobinopathies.. Canadian Family Physician. 30:1873-1876. 1984
- The Intrauterine Diagnosis of Hemoglobin Disorders. Clinics in Perinatology. 11:283-308. 1984
- Hb J-Singa (α-78 Asn → Asp), A newly discovered hemoglobin variant with the same amino acid substitution as one of the two present in Hb J-Singapore (α-78 Asn → Asp, α-79 Ala → Gly). Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 784:187-188. 1984
- Hemoglobin Hamilton or α2β211(a8)Val→Ile: A silent β‐chain variant detected by triton X‐100 acid‐urea polyacrylamide gel electrophoresis. American Journal of Hematology. 16:47-52. 1984
- The Way We Teach… Haematology to Postgraduates. Medical Teacher. 6:134-137. 1984
- The Way We Teach… Haematology to Undergraduates. Medical Teacher. 6:92-96. 1984
- The value of elevated gamma globulins in the diagnosis of monoclonal gammopathy and multiple myeloma. Irish Journal of Medical Science. 152:349-352. 1983
- Hemoglobin E diseases: Hematological, analytical, and biosynthetic studies in homozygotes and double heterozygotes for α‐thalassemia. American Journal of Hematology. 13:15-21. 1982
- Cimetidine potentiation of warfarin action.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 126:116. 1982
- HEMOGLOBINOPATHIES IN THE HAMILTON AREA - A 10 YEAR SURVEY WITH EMPHASIS ON THEIR CLINICAL-SIGNIFICANCE. Canadian journal of medical technology. 44:17-20. 1982
- HEMOGLOBINOPATHIES IN THE HAMILTON REGION - STUDY DISTRIBUTED OVER 10 YEARS WITH THE EMPHASIS ON CLINICAL-APPLICATION. Canadian journal of medical technology. 44:21-24. 1982
- Hemoglobinopathies in Canada. Hemoglobin. 6:235-241. 1982
- Preservation of platelets during extracorporeal circulation in sheep. A comparison between aspirin and sulfinpyrazone.. Circulation Research. 49:452-457. 1981
- DETECTION OF LEUCOCYTES IN PERITONEAL EFFLUENT BY TEST STRIP. The Lancet. 317:437-438. 1981
- Sickle Cell Traits in Canada. Acta Haematologica. 65:157-163. 1981
- Identification of hemoglobin E by the isopropanol solubility test. Clinical Biochemistry. 13:146-148. 1980
- A New Case of the Unstable Haemoglobin Genova(α<sub>2</sub>β<sub>2</sub>28(β 10)Leu→Pro) in Canada: As a Result of Sporadic Mutation and Causing Heinz Body Haemolytic Anaemia. Acta Haematologica. 63:222-225. 1980
- Haemoglobin D Los Angeles, D-β<sup>+</sup>-Thalassaemia, and D-β°- Thalassaemia. Acta Haematologica. 63:151-155. 1980
- Laboratory diagnosis of HB CC-α-thalassemia. Clinical Biochemistry. 12:157-158. 1979
- The direct assay for platelet-associated IgG (PAIgG): lack of association between antibody level and platelet size. Blood. 53:73-80. 1979
- Iron deficiency in inflammatory bowel disease. Digestive Diseases and Sciences. 23:705-709. 1978
- Preleukaemia and Reticulocytosis: A Case Report with in Vitro Evidence for Abnormal Reticulocyte Maturation. European Journal of Haematology. 20:417-422. 1978
- A Second Patient with Hemoglobin Alberta, a High-Oxygen-Affinity Variant Causing Erythrocytosis and Forming Asymmetric Tetramers. Hemoglobin. 2:557-559. 1978
- Hemolytic Anemia in Patients Receiving Sulfasalazine. Digestion. 17:503-508. 1978
- Cellular composition of peritoneal effluent: response to bacterial peritonitis.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 117:1061-1062. 1977
- Diagnosis of Intravascular Haemolysis Using Starch Gel Electrophoresis. European Journal of Haematology. 19:343-346. 1977
- Megaloblastic anemia in patients receiving total parenteral nutrition without folic acid or vitamin B12 supplementation.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 117:144-146. 1977
- THE MOLECULAR COMPONENTS OF HUMAN TRANSFERRIN TYPE C. Chemical Biology and Drug Design. 10:17-26. 1977
- A Radioimmunoassay for Serum Ferritin. Clinical Chemistry. 23:683-689. 1977
- "Blood and guts": one component of an integrated program in biologic sciences as applied to medicine.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 116:59-62. 1977
- Effect of Lead on Globin Synthesisin Vitro. American Journal of Clinical Pathology. 67:77-79. 1977
- A study of phosphoglycerate kinase in human erythrocytes. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 445:89-103. 1976
- A study of phosphoglycerate kinase in human erythrocytes. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 445:74-88. 1976
- Hemoglobin QIndia, α64(E l3) Asp→His, and β- Thalassemiaina Canadian Family. American Journal of Clinical Pathology. 66:446-448. 1976
- HemoglobiriBethesda, β145 (HC2) Tyr→His, in a Canadian Family. American Journal of Clinical Pathology. 66:449-452. 1976
- The Patterns of Fetal Haemoglobin Production in Leukaemia. British Journal of Haematology. 32:487-506. 1976
- Massive colchicine overdose: a report on the toxicity. American Journal of the Medical Sciences. 271:233-238. 1976
- Ethanol Inhibition of Haemoglobin Synthesis: In Vitro Evidence for a Haem Correctable Defect in Normal Subjects and in Alcoholics. British Journal of Haematology. 28:311-316. 1974
- Erythrocyte Coproporphyrin and Protoporphyrin in Ethanol-induced Sideroblastic Erythropoiesis. Blood. 43:291-295. 1974
- Globin Synthesis in Sideroblastic Anaemia I α AND β PEPTIDE CHAIN SYNTHESIS. British Journal of Haematology. 20:263-275. 1971
- Alpha- and beta- peptide chain synthesis in sideroblastic anaemia.. British Journal of Haematology. 17:607-608. 1969