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HemoglobiriBethesda, β145 (HC2) Tyr→His, in a...
Journal article

HemoglobiriBethesda, β145 (HC2) Tyr→His, in a Canadian Family

Abstract

A hemoglobin mutant with the mobility of hemoglobin (Hb) A on alkaline cellulose acetate or starch gel electrophoresis and mobility between Hb A and Hb S on citrate agar electrophoresis was detected in a patient with erythrocytosis. Structural analysis shows a substitution of histidine by tyrosine at position 145 in the beta-chain.

Authors

Schmidt RM; Jue DL; Ali MAM; Lyonnais J; Moo-Penn WF

Journal

American Journal of Clinical Pathology, Vol. 66, No. 2, pp. 449–452

Publisher

Oxford University Press (OUP)

Publication Date

August 1, 1976

DOI

10.1093/ajcp/66.2.449

ISSN

0002-9173