HemoglobiriBethesda, β145 (HC2) Tyr→His, in a Canadian Family Academic Article uri icon

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  • A hemoglobin mutant with the mobility of hemoglobin (Hb) A on alkaline cellulose acetate or starch gel electrophoresis and mobility between Hb A and Hb S on citrate agar electrophoresis was detected in a patient with erythrocytosis. Structural analysis shows a substitution of histidine by tyrosine at position 145 in the beta-chain.


  • Schmidt, Robert M
  • Jue, Danny L
  • Ali, Mahmoud
  • Lyonnais, Jean
  • Moo-Penn, Winston F

publication date

  • August 1, 1976