Journal article
A Randomized, Double-Blind, Placebo-Controlled Crossover Study of the Effect of Exogenous Melatonin on Delayed Sleep Phase Syndrome
Abstract
OBJECTIVE: The effects of exogenous melatonin on sleep, daytime sleepiness, fatigue, and alertness were investigated in 22 patients with delayed sleep phase syndrome whose nocturnal sleep was restricted to the interval from 24:00 to 08:00 hours. This study was a randomized, double-blind, placebo-controlled crossover trial. Subjects received either placebo or melatonin (5 mg) daily for 4 weeks, underwent a 1-week washout period, and then were …
Authors
Kayumov L; Brown G; Jindal R; Buttoo K; Shapiro CM
Journal
Biopsychosocial Science and Medicine, Vol. 63, No. 1, pp. 40–48
Publisher
Wolters Kluwer
Publication Date
January 2001
DOI
10.1097/00006842-200101000-00005
ISSN
2998-8748