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Abstract

The hypothesis that the neuromuscular blocking potency of pancuronium and vecuronium depends on the two acetylcholine moieties present at positions 3 and 17 was tested in cats by examining the neuromuscular profile of several desacetoxy analogues. Blockade of sciatic nerve-induced contraction of the tibialis and soleus muscles, as well as the effects on vagal-induced bradycardia and on sympathetically induced contractions of the nictitating …

Authors

Bowman WC; Rodger IW; Houston J; Marshall RJ; Mclndewar I

Journal

Anesthesiology, Vol. 69, No. 1, pp. 57–62

Publisher

Wolters Kluwer

Publication Date

July 1, 1988

DOI

10.1097/00000542-198807000-00009

ISSN

0003-3022