selected scholarly activity
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chapters
- Airway Smooth Muscle Cells. 89-112. 1998
- Future Therapies for Asthma. 795-819. 1998
- Inducible Cyclooxygenase (COX-2). 355-371. 1998
- Preface. v-vi. 1998
- Voltage-Dependent and Receptor-Operated Calcium Channels. 155-168. 1995
- Calcium ION Mechanisms in Airway Smooth Muscle: Potential Targets for Novel Symptomatic Drugs for Asthma. 69-87. 1988
- Is the Cardiotonic Effect of Aminopyridines and Aminopyrimidines in vitro A Consequence of Increased Extracellular pH?. 278-278. 1982
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conferences
- Cyclooxygenase-2 (COX-2) in acute myocardial infarction: cellular expression and use of selective COX-2 inhibitor. Canadian Journal of Physiology and Pharmacology. 114-119. 2003
- Increased cyclooxygenase-2 (COX-2) expression in acute myocardial infarction: Therapeutic target of a selective COX-2 inhibitor. Circulation. 271-271. 2000
- Inhibition of cyclooxygenase-2 prevents myocardial dysfunction and improves cardiomyocyte survival in ischemic heart failure. Circulation. 200-200. 2000
- Rofecoxib, (MK-966, VIOXXa), a hew, selective, and orally active cyclooxygenase-2 inhibitor.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U1008-U1008. 1999
- Potent, selective, and orally active second generation COX-2 inhibitors.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. U861-U861. 1998
- Comparative study of histamine, leukotriene D-4 (LTD4) and ascaris-induced changes in lung resistance (R-L) in propofol (Rapinovet (R))-anesthetised non human primates. Naunyn-Schmiedeberg's Archives of Pharmacology. R326-R326. 1998
- Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV).. Naunyn-Schmiedeberg's Archives of Pharmacology. R661-R661. 1998
- Inhibition of [H-3]-noradrenaline release from isolated human atrial appendages by interleukin-1 beta involves the cyclooxygenase-2 pathway. Naunyn-Schmiedeberg's Archives of Pharmacology. R598-R598. 1998
- Effects of phosphodiesterase IV inhibitors on human polymorphonuclear cells chemotaxis.. The FASEB Journal. 1758-1758. 1997
- Discovery of new class of potent and selective COX-2 inhibitors.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 16-MEDI. 1996
- New potent and selective inhibitors of the COX-2 enzyme.. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 141-MEDI. 1996
- CIGARETTE SMOKE-INDUCED BRONCHOCONSTRICTION IN GUINEA-PIGS - CHOLINERGIC AND NONCHOLINERGIC MECHANISMS. The FASEB Journal. A697-A697. 1995
- CAPSAICIN PULMONARY CONSTRICTION IS INHIBITED BY COMBINED NK1 AND NK2 ANTAGONISTS IN TRACHEAL PERFUSED GUINEA-PIG LUNGS. American Review of Respiratory Disease. A706-A706. 1993
- EFFECT OF THE SELECTIVE LEUKOTRIENE-D(4) RECEPTOR ANTAGONIST, L-660,711 (MK-0571), ON SPECIFIC AIRWAY-RESISTANCE (SRAW) IN CONSCIOUS SQUIRREL-MONKEYS USING A NONINVASIVE PLETHYSMOGRAPHIC TECHNIQUE. American Review of Respiratory Disease. A179-A179. 1993
- INVOLVEMENT OF NK1 AND NK2 RECEPTORS IN PULMONARY RESPONSES ELICITED BY NONADRENERGIC, NONCHOLINERGIC (NANC) VAGAL-STIMULATION IN ANESTHETIZED GUINEA-PIGS. American Review of Respiratory Disease. A708-A708. 1993
- MUSCARINIC CHOLINERGIC AND ALPHA-ADRENERGIC INHIBITION OF ACETYLCHOLINE (ACH) RELEASE IN GUINEA-PIG TRACHEA - ROLE OF IBERIOTOXIN-SENSITIVE K+ CHANNELS. American Review of Respiratory Disease. A504-A504. 1993
- NK1 AND NK2 RECEPTORS MEDIATE NEUROKININ-INDUCED AND RESINIFERATOXIN-INDUCED BRONCHOCONSTRICTION IN ANESTHETIZED GUINEA-PIGS. American Review of Respiratory Disease. A710-A710. 1993
- NK(1) AND NK(2) RECEPTORS DISPLAY DIFFERENT PROFILES IN MEDIATING PLASMA EXTRAVASATION IN GUINEA-PIG AIRWAYS. The FASEB Journal. A830-A830. 1993
- POTASSIUM CHANNELS IN THP-1 HUMAN MONOCYTES. Biophysical Journal. A200-A200. 1993
- AIRWAY SMOOTH MUSCLE - SIGNAL TRANSDUCTION AND CONTRACTILE MECHANISMS. ASTHMA. 243-257. 1993
- EFFECTS OF HISTAMINE ON CAMP, CAMP-DEPENDENT PROTEIN-KINASE ACTIVITY, CGMP AND INOSITOL TRISPHOSPHATE IN AIRWAY SMOOTH-MUSCLE. British Journal of Pharmacology. P510-P510. 1988
- ORG10325, A NEW CARDIOTONIC AGENT WITH POSITIVE INOTROPIC AND VASODILATOR PROPERTIES. British Journal of Pharmacology. P488-P488. 1988
- Lack of turnover of inositol phosphates in guinea-pig and rat lung parenchyma may be due to its dependence on extracellular calcium during contraction. Biochemical Society Transactions. 35-36. 1988
- Inositol lipid turnover in isolated guinea-pig trachealis and lung parenchyma. Biochemical Society Transactions. 474-474. 1987
- HUMAN INVITRO BRONCHIAL SMOOTH-MUSCLE RESPONSES TO LEUKOTRIENE D-4 IN RELATION TO THE QUANTITY OF MUSCLE. Thorax. 734-734. 1986
- COMPARISON OF INVIVO AIRWAY RESPONSIVENESS AND INVITRO SMOOTH-MUSCLE SENSITIVITY TO LEUKOTRIENE-D4 IN MAN. American Review of Respiratory Disease. A116-A116. 1986
- DOES NALOXONE RELAX AIRWAY SMOOTH-MUSCLE. British Journal of Clinical Pharmacology. P116-P116. 1986
- DOES THROMBOXAN-A2 MEDIATE THE INDIRECT CONTRACTILE EFFECT OF LEUCOTRIENE-D4 IN GUINEA-PIG LUNG PARENCHYMA. Thorax. 713-713. 1985
- EFFECT OF VERAPAMIL ON LEUCOTRIENE-D4 INDUCED BRONCHOCONSTRICTION IN ASTHMATIC-PATIENTS. Thorax. 714-715. 1985
- EFFECTS OF LEUCOTRIENE-D4 AND OTHER AGONISTS ON CA-45 EFFLUX FROM AIRWAY SMOOTH-MUSCLE. Thorax. 713-713. 1985
- VERAPAMIL INHIBITS LEUKOTRIENE D-INDUCED BRONCHOCONSTRICTION IN NORMAL SUBJECTS. Thorax. 217-218. 1985
- VERAPAMIL INHIBITS LEUKOTRIENE-D4 INDUCED BRONCHOCONSTRICTION INVIVO. Scottish Medical Journal. 192-193. 1985
- Forskolin inhibits leukotriene D4-induced thromboxane B2 release from guinea-pig lung parenchyma. Prostaglandins. 651-651. 1984
- EFFECT OF PASSIVE SENSITIZATION OF HUMAN BRONCHIAL SMOOTH-MUSCLE ON INVITRO SENSITIVITY TO HISTAMINE. Thorax. 698-698. 1984
- INVIVO AND INVITRO AIRWAY RESPONSIVENESS IN MAN. European Journal of Respiratory Diseases. 502-502. 1983
- RELATIONSHIP BETWEEN INVIVO AIRWAY RESPONSIVENESS AND INVITRO SMOOTH-MUSCLE SENSITIVITY TO METHACHOLINE IN MAN. Thorax. 705-706. 1983
- EFFECTS OF CA2+ WITHDRAWAL AND VERAPAMIL ON EXCITATION-CONTRACTION COUPLING IN SENSITIZED GUINEA-PIG AIRWAY SMOOTH-MUSCLE. British Journal of Pharmacology. P175-P176. 1981
- EFFECTS OF INCREASED PH ON CONTRACTILE-FORCE OF RABBIT ISOLATED PAPILLARY-MUSCLES. British Journal of Pharmacology. P295-P295. 1981
- HYPER-REACTIVITY OF GUINEA-PIG ISOLATED AIRWAY SMOOTH-MUSCLE. British Journal of Pharmacology. P180-P181. 1981
- POSITIVE INOTROPISM AND CYCLIC-NUCLEOTIDES IN MAMMALIAN CARDIAC-MUSCLE. British Journal of Pharmacology. P939-P939. 1981
- PROSTAGLANDIN-F2-ALPHA, THROMBOXANE AND THE ACUTE RESPONSE TO ESCHERICHIA-COLI ENDOTOXIN IN ANESTHETIZED CATS. British Journal of Pharmacology. P792-P793. 1981
- EXCITATION-CONTRACTION COUPLING IN SENSITIZED GUINEA-PIG AIRWAY SMOOTH-MUSCLE. The FASEB Journal. 296-296. 1980
- Effects of Ca2+ withdrawal and verapamil on excitation-contraction coupling in rabbit pulmonary vascular smooth muscle [proceedings].. British Journal of Pharmacology. 467P. 1979
- Effect of 4-aminopyridine on muscle contractility in the cat [proceedings].. British Journal of Pharmacology. 466P-467P. 1979
- SOURCES OF ACTIVATOR CALCIUM FOR PHENYLEPHRINE (PE) INDUCED CONTRACTION OF PULMONARY VASCULAR SMOOTH-MUSCLE. The FASEB Journal. 604-604. 1979
- DIFFERENTIATION OF CALCIUM CHANNELS IN PULMONARY VASCULAR SMOOTH-MUSCLE. PHARMACOLOGIST. 227-227. 1978
- MODULATING INFLUENCE OF SODIUM ON RESTING TENSION (RT) AND RELAXATION IN RABBIT AORTIC SMOOTH-MUSCLE. PHARMACOLOGIST. 227-227. 1978
- ROLE OF CALCIUM IN ALPHA-ADRENOCEPTOR-MEDIATED CONTRACTION OF PULMONARY VASCULAR SMOOTH-MUSCLE. The FASEB Journal. 794-794. 1978
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journal articles
- Evidence against the Involvement of Chronic Cerebrospinal Venous Abnormalities in Multiple Sclerosis. A Case-Control Study. PLoS ONE. 8:e72495-e72495. 2013
- Actions of the muscle relaxant chandonium iodide on guinea-pig ileum and vas deferens preparations. Journal of Pharmacy and Pharmacology. 28:617-619. 2011
- Actions of the sympathomimetic bronchodilator, AQL208, on the cardiovascular, bronchiolar and skeletal muscle systems of the cat. Journal of Pharmacy and Pharmacology. 23:226S-226S. 2011
- Does naloxone induce relaxation of guinea-pig airway smooth muscle?. Journal of Pharmacy and Pharmacology. 38:702-705. 2011
- Enhancement of Amrinone-induced Positive Inotropy in Rabbit Papillary Muscles with Depressed Contractile Function: Effects on Cyclic Nucleotide Levels and Phosphodiesterase Isoenzymes. Journal of Pharmacy and Pharmacology. 43:88-94. 2011
- Involvement of NK1 and NK2 Receptors in Pulmonary Responses Elicited by Non-adrenergic, Non-cholinergic Vagal Stimulation in Guinea-pigs. Journal of Pharmacy and Pharmacology. 47:914-920. 2011
- The Inotropic Effect of 4−Aminopyridine and pH Changes in Rabbit Papillary Muscle. Journal of Pharmacy and Pharmacology. 41:601-606. 2011
- Analgesic targets: today and tomorrow. Inflammopharmacology. 17:151-161. 2009
- Correction to: J. Zacher, D. Feldman, R. Gerli et al. A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis. Curr Med Res Opin 2003; 19(8): 725-736.. Current Medical Research and Opinion. 20:1689-1690. 2004
- Inhibition of COX pathway in experimental myocardial infarction. Journal of Molecular and Cellular Cardiology. 37:71-77. 2004
- Inhibition of COX pathway in experimental myocardial infarction.. Journal of Molecular and Cellular Cardiology. 37:71-77. 2004
- A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis. Current Medical Research and Opinion. 19:725-736. 2003
- Corrigendum to “Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret”. Neuropharmacology. 40:465-465. 2001
- Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.. Journal of Pharmacology and Experimental Therapeutics. 296:558-566. 2001
- Erratum: Selective potentiating effect of RS14203 on a serotoninergic pathway in anesthetized rats. Canadian Journal of Physiology and Pharmacology. 79:93-93. 2001
- Selective potentiating effect of RS14203 on a serotoninergic pathway in anesthetized rats (vol 78, pg 708, 2000). Canadian Journal of Physiology and Pharmacology. 79:93-93. 2001
- Selective potentiating effect of RS14203 on a serotoninergic pathway in anesthetized rats. Canadian Journal of Physiology and Pharmacology. 78:708-713. 2000
- Inhibition of Cyclooxygenase-2 Improves Cardiac Function in Myocardial Infarction. Biochemical and Biophysical Research Communications. 273:772-775. 2000
- From Bench to Bedside. American Journal of Respiratory and Critical Care Medicine. 161:S7-S10. 2000
- Prostaglandin H Synthase 2 Expression in Airway Cells from Patients with Asthma and Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 161:636-640. 2000
- Evidence of the existence of G(i)-coupled inhibitory modulation of adenylyl cyclase by muscarinic receptor in guinea-pig trachealis. Journal of the Chemical Society of Pakistan. 21:321-326. 1999
- Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.. Journal of Pharmacology and Experimental Therapeutics. 290:551-560. 1999
- The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor. Bioorganic and Medicinal Chemistry Letters. 9:1773-1778. 1999
- Role of Leukotrienes and Leukotriene Receptor Antagonists in Asthma. Pulmonary Pharmacology and Therapeutics. 12:107-110. 1999
- Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret. Neuropharmacology. 38:289-297. 1999
- The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor‐α and leukotriene B4 in a novel human whole blood assay. British Journal of Pharmacology. 126:979-988. 1999
- Differential Effect of a Selective Cyclooxygenase-2 Inhibitor Versus Indomethacin on Renal Blood Flow in Conscious Volume-Depleted Dogs. Journal of Cardiovascular Pharmacology. 32:686-694. 1998
- Leukotrienes and the brain. The Lancet. 352:1487-1488. 1998
- Role of tachykinins in airway responses to ozone in rats. Journal of applied physiology. 85:442-450. 1998
- Induction of Cyclooxygenase-2 and Activation of Nuclear Factor-κB in Myocardium of Patients With Congestive Heart Failure. Circulation. 98:100-103. 1998
- Co-localization of the Cysteine Protease Caspase-3 with Apoptotic Myocytes afterIn VivoMyocardial Ischemia and Reperfusion in the Rat. Journal of Molecular and Cellular Cardiology. 30:733-742. 1998
- Characterization of CHO-K1 cells stably expressing PDE-IV enzymes. Cell Biochemistry and Biophysics. 29:159-178. 1998
- Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma. Canadian Journal of Physiology and Pharmacology. 76:210-217. 1998
- Cardiovascular and Renal Actions of the EndothelinB Receptor in Pigs. Journal of Cardiovascular Pharmacology. 29:704-712. 1997
- A selective inhibitor of cyclooxygenase-2 reverses endotoxin-induced pyretic responses in non-human primates. European Journal of Pharmacology. 327:221-225. 1997
- Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor. British Journal of Pharmacology. 121:105-117. 1997
- Role of leukotrienes and leukotriene receptor antagonist in asthma: new advances.. Journal of Investigational Allergology and Clinical Immunology. 7:279. 1997
- Selective Cyclooxygenase-2 Inhibitors as Potential Therapeutic Agents for Inflammatory Diseases. Advances in Experimental Medicine and Biology. 407:157-161. 1997
- Methods for studying experimental myocardial ischemic and reperfusion injury. Journal of Pharmacological and Toxicological Methods. 35:179-190. 1996
- A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors. Inflammation Research. 45:68-74. 1996
- One-Month Exposure to Inhaled Endotoxin Produces a Dose-Dependent Increase in Stored Mucosubstances in Rat Intrapulmonary Airways. Experimental Lung Research. 22:509-523. 1996
- Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach.. Journal of Pharmacology and Experimental Therapeutics. 274:1531-1537. 1995
- Effect of dexamethasone on antigen-induced high molecular weight glycoconjugate secretion in allergic guinea pigs.. American Journal of Respiratory Cell and Molecular Biology. 13:133-143. 1995
- Neurokinin receptors subserving plasma extravasation in guinea pig airways. Canadian Journal of Physiology and Pharmacology. 73:927-931. 1995
- Cigarette smoke-induced bronchoconstriction: cholinergic mechanisms, tachykinins, and cyclooxygenase products. Journal of applied physiology. 78:2260-2266. 1995
- Erratum: Pharmacology of montelukast sodium (Singulair™), a potent and selective leukotriene D4 receptor antagonist. Canadian Journal of Physiology and Pharmacology. 73:747-747. 1995
- Increased airway responsiveness to inhaled methacholine in a rat model of chronic bronchitis.. American Journal of Respiratory and Critical Care Medicine. 151:1931-1938. 1995
- PROLIFERATION OF GUINEA-PIG TRACHEAL EPITHELIAL-CELLS IN COCULTURE WITH RAT DORSAL-ROOT GANGLION NEURAL CELLS. American Journal of Physiology. 268:L957-L965. 1995
- Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells. American Journal of Physiology - Lung Cellular and Molecular Physiology. 268:L957-L965. 1995
- Substance P-induced histamine release in tracheally perfused guinea pig lungs. Journal of applied physiology. 78:1234-1241. 1995
- Pharmacology of montelukast sodium (Singulair™), a potent and selective leukotriene D4receptor antagonist. Canadian Journal of Physiology and Pharmacology. 73:191-201. 1995
- L-745,337: A selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats. Neuropharmacology. 33:1609-1611. 1994
- Dual Cardiovascular Effects of Endothelin-1 Dissociated by BQ-153, a Novel ETA Receptor Antagonist. Journal of Cardiovascular Pharmacology. 24:587-594. 1994
- Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells. Canadian Journal of Physiology and Pharmacology. 72:1025-1030. 1994
- Hypertrophic and hyperplastic changes of mucus-secreting epithelial cells in rat airways: assessment using a novel, rapid, and simple technique.. American Journal of Respiratory Cell and Molecular Biology. 10:625-634. 1994
- Leukotriene D4-induced increases in cytosolic calcium in THP-1 cells: dependence on extracellular calcium and inhibition with selective leukotriene D4 receptor antagonists.. Journal of Pharmacology and Experimental Therapeutics. 269:891-896. 1994
- Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs.. American Journal of Respiratory and Critical Care Medicine. 149:1175-1179. 1994
- Neurokinin (NK2) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea. Canadian Journal of Physiology and Pharmacology. 72:182-188. 1994
- Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique. Canadian Journal of Physiology and Pharmacology. 72:11-18. 1994
- Identification of both NK1 and NK2 receptors in guinea‐pig airways. British Journal of Pharmacology. 110:693-700. 1993
- NK1and NK2Receptors Mediate Tachykinin and Resiniferatoxin-induced Bronchospasm in Guinea Pigs. American Journal of Respiratory and Critical Care Medicine. 148:915-921. 1993
- Neurokinin receptor mediated plasma extravasation in guinea pig and rat airways: comparison of 125I-labelled human fibrinogen and 99mTc-labelIed human serum albumin as markers of leakage. Canadian Journal of Physiology and Pharmacology. 71:506-511. 1993
- Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs.. Journal of Clinical Investigation. 92:315-323. 1993
- Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea‐pig lung parenchyma. British Journal of Pharmacology. 108:824-832. 1993
- NK2 receptors mediate plasma extravasation in guinea‐pig lower airways. British Journal of Pharmacology. 108:383-386. 1993
- Muscarinic blockade of β‐adrenoceptor‐stimulated adenylyl cyclase: the role of stimulatory and inhibitory guanine‐nucleotide binding regulatory proteins (Gs and Gi). British Journal of Pharmacology. 107:881-887. 1992
- The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung. Biochemical Journal. 283:487-491. 1992
- The effect of methacholine and histamine on cyclic AMP-dependent protein kinase activity in the guinea-pig isolated trachea. Canadian Journal of Physiology and Pharmacology. 70:344-348. 1992
- Airway smooth muscle. British Medical Bulletin. 48:97-107. 1992
- Phorbol esters trigger the inactivation of the inhibitory guanine-nucleotide binding regulatory protein (Gi) in airway smooth muscle. Biochemical Society Transactions. 19:75S-75S. 1991
- The metabolism of leukotrienes, detoxification of reactive oxygen species and the activity of the cytochrome P450 mixed function oxidase system in sensitised guinea-pig lungs. Pulmonary Pharmacology and Therapeutics. 4:165-169. 1991
- NORADRENALINE SENSITIVITY AND CALCIUM FLUXES IN ARTERIES FROM RABBITS WITH PERINEPHRITIS HYPERTENSION. Clinical and Experimental Pharmacology and Physiology. 17:531-543. 1990
- Determination of soluble CAMP-dependent protein kinase activity in guinea-pig tracheal smooth muscle. Biochemical Pharmacology. 39:1365-1374. 1990
- Excitation-contraction coupling mechanisms in airway smooth muscle: new targets in drug design.. Drug Design and Discovery. 5:169-193. 1990
- The effect of M&B 22948 on methacholine‐ and histamine‐induced contraction and inositol 1,4,5‐trisphosphate levels in guinea‐pig tracheal tissue. British Journal of Pharmacology. 98:336-338. 1989
- Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition. British Journal of Pharmacology. 98:291-301. 1989
- Mediators of acute lung injury in endotoxaemia.. Progress in Clinical and Biological Research. 308:357-369. 1989
- Preservatives in the vehicle of naloxone: pharmacological effects. Biomedicine and Pharmacotherapy. 43:771-777. 1989
- Characterisation of receptors mediating the contractile effects of prostanoids in guinea-pig and human airways. European Journal of Pharmacology. 153:149-159. 1988
- Effects of leukotriene D4 on the mechanical and electrical properties of guinea‐pig isolated trachealis. British Journal of Pharmacology. 94:729-736. 1988
- Structure. Anesthesiology. 69:57-62. 1988
- Calcium ION Mechanisms in Airway Smooth Muscle: Potential Targets for Novel Symptomatic Drugs for Asthma. Agents and Actions Supplements. 23:69-87. 1988
- Concentration-related differences in the effects of the Ca2+ agonist Bay K 8644 in human bronchus in vitro. Vascular Pharmacology. 19:399-402. 1988
- Effects of phosphodiesterase inhibitors on normal and chemically‐skinned isolated airway smooth muscle. British Journal of Pharmacology. 92:673-681. 1987
- INVIVO AND INVITRO HUMAN AIRWAY RESPONSIVENESS TO LEUKOTRIENE-D4 IN PATIENTS WITHOUT ASTHMA. Journal of Allergy and Clinical Immunology. 80:688-694. 1987
- In vivo and in vitro human airway responsiveness to leukotriene D4 in patients without asthma. Journal of Allergy and Clinical Immunology. 80:688-694. 1987
- Calcium Channels. American Journal of Respiratory and Critical Care Medicine. 136:S15-S17. 1987
- Preface. American Journal of Respiratory and Critical Care Medicine. 136:v-v. 1987
- Does thromboxane mediate the indirect contractile action of leukotriene D4 in guinea-pig isolated lung parenchyma under equilibrium conditions?. Canadian Journal of Physiology and Pharmacology. 65:1467-1477. 1987
- Electrophysiological and other aspects of excitation-contraction coupling and uncoupling in mammalian airway smooth muscle. Life Sciences. 41:111-132. 1987
- Leukotriene antagonist FPL 57231 prevents the acute pulmonary effects of Escherichia coli endotoxin in cats.. Journal of Inflammation. 21:155-168. 1987
- Sr2+ may differentiate high and low affinity Ca2+ stores in guinea-pig trachealis. Vascular Pharmacology. 18:605-608. 1987
- Effect of verapamil and sodium cromoglycate on leukotriene D4 induced bronchoconstriction in patients with asthma.. Thorax. 41:753-758. 1986
- The dependence of airway smooth muscle on extracellular Ca2+ for contraction is influenced by the presence of cartilage. Life Sciences. 38:1499-1505. 1986
- Agonist-induced contractile responses of human bronchial muscle in vitro: Effects of Ca2+ removal, La3+ and PY108068. European Journal of Pharmacology. 121:251-255. 1986
- Desensitization of platelet α2-adrenoceptors after short term infusions of adrenoceptor agonist in man. Clinical Science. 70:147-153. 1986
- In vitro and in vivo effect of verapamil on human airway responsiveness to leukotriene D4.. Thorax. 41:12-16. 1986
- Airway responsiveness to histamine in man: effect of atropine on in vivo and in vitro comparison.. Thorax. 40:261-267. 1985
- Excitation‐contraction coupling and uncoupling in airway smooth muscle.. British Journal of Clinical Pharmacology. 20:255S-266S. 1985
- Cyclic nucleotides and contractility of isolated soleus muscle.. British Journal of Pharmacology. 84:259-264. 1985
- The relationship between coronary artery occlusion-induced arrhythmias and myocardial cyclic nucleotide levels in the anaesthetized rat.. British Journal of Pharmacology. 84:139-145. 1985
- Comparison of in vivo airway responsiveness and in vitro smooth muscle sensitivity to methacholine in man.. Thorax. 39:837-843. 1984
- Lack of effect of leukotriene D4 on Ca‐uptake in airway smooth muscle. British Journal of Pharmacology. 83:499-504. 1984
- Forskolin, cyclic nucleotides and positive inotropism in isolated papillary muscles of the rabbit. British Journal of Pharmacology. 81:151-159. 1984
- The effect of a selective 5‐HT2 antagonist, ketanserin, on the pulmonary responses to Escherichia coli endotoxin. British Journal of Pharmacology. 80:295-301. 1983
- The release of prostanoids during the acute pulmonary response to E. coli endotoxin in anaesthetized cats. British Journal of Pharmacology. 78:561-570. 1983
- Actions of 4-Aminopyridine on the Cardiovascular Systems of Anaesthetized Cats and Dogs. Survey of Anesthesiology. 26:326-327. 1982
- DIRECT ACTION OF 4-AMINOPYRIDINE ON THE CONTRACTILITY OF A FAST-CONTRACTING MUSCLE IN THE CAT. Clinical and Experimental Pharmacology and Physiology. 9:21-34. 1982
- ACTIONS OF 4-AMINOPYRIDINE ON THE CARDIOVASCULAR SYSTEMS OF ANAESTHETIZED CATS AND DOGS. British Journal of Anaesthesia. 53:555-565. 1981
- SODIUM‐DEPENDENT RELAXATION IN ARTERIAL SMOOTH MUSCLE *. Clinical and Experimental Pharmacology and Physiology. 8:209-214. 1981
- Effects of dantrolene sodium on respiratory and other muscles and on respiratory parameters in the anaesthetised cat. European Journal of Pharmacology. 55:293-303. 1979
- Actions of two dopamine derivatives at adreno- and cholinoceptors. Journal of Medicinal Chemistry. 22:117-119. 1979
- Neuromuscular blocking activity of two fractions isolated from the venom of the seasnake, Laticauda semifasciata. Toxicon. 16:45-50. 1978
- Reversibility of neuromuscular blockade produced by toxins isolated from the venom of the seasnake Laticauda semifasciata. Toxicon. 16:219-225. 1978
- Some actions of chandonium iodide, a new short‐acting muscle relaxant, in anaesthetized cats and on isolated muscle preparations. Clinical and Experimental Pharmacology and Physiology. 2:159-170. 1975
- ACTIONS OF THE SYMPATHOMIMETIC BRONCHODILATOR, TRIMETOQUINOL (AQL 208) ON THE CARDIAC, RESPIRATORY AND SKELETAL MUSCLE SYSTEMS IN THE ANAESTHETIZED CAT, AND ON CAT ISOLATED ATRIAL AND TRACHEAL PREPARATIONS. Clinical and Experimental Pharmacology and Physiology. 1:401-413. 1974
- USE OF CUMULATIVE DOSE-RESPONSE CURVES IN POTENCY COMPARISONS OF SYMPATHOMIMETIC AMINES ON PULMONARY RESISTANCE IN ANAESTHETIZED CATS. Clinical and Experimental Pharmacology and Physiology. 1:211-217. 1974
- Effects of isoetharine on airways resistance, heart rate, and contractions of the soleus muscle of the anaesthetised cat. European Journal of Pharmacology. 24:211-217. 1973
- Pharmacological actions of a new β‐adrenoceptor agonist, MJ‐9184–1, in anaesthetized cats. British Journal of Pharmacology. 46:375-385. 1972
- Actions of the sympathomimetic bronchodilator, rimiterol (R798), on the cardiovascular, respiratory and skeletal muscle systems of the anaesthetized cat.. British Journal of Pharmacology. 45:574-583. 1972