Journal article
Dietary galactose inhibits GDF-9 mediated follicular development in the rat ovary
Abstract
Clinical evidence suggests an association between galactosemia and premature ovarian failure, but the mechanism is still not fully understood. Growth differentiation factor-9 (GDF-9) is thought to be an obligatory growth factor during the gonadotropin-independent phase of folliculogenesis. The objective of this study was to examine the effects of galactose on initiation of folliculogenesis in the peripubertal interval and the connection between …
Authors
Liu G; Shi F; Blas-Machado U; Yu R; Davis VL; Foster WG; Magoffin DA; Hughes CL
Journal
Reproductive Toxicology, Vol. 21, No. 1, pp. 26–33
Publisher
Elsevier
Publication Date
January 2006
DOI
10.1016/j.reprotox.2005.07.001
ISSN
0890-6238