Journal article
Sequence overlap between autosomal and sex-linked probes on the Illumina HumanMethylation27 microarray
Abstract
The Illumina Infinium HumanMethylation27 BeadChip (Illumina 27k) microarray is a high-throughput platform capable of interrogating the human DNA methylome. In a search for autosomal sex-specific DNA methylation using this microarray, we discovered autosomal CpG loci showing significant methylation differences between the sexes. However, we found that the majority of these probes cross-reacted with sequences from sex chromosomes. Moreover, we …
Authors
Chen Y-A; Choufani S; Ferreira JC; Grafodatskaya D; Butcher DT; Weksberg R
Journal
Genomics, Vol. 97, No. 4, pp. 214–222
Publisher
Elsevier
Publication Date
April 2011
DOI
10.1016/j.ygeno.2010.12.004
ISSN
0888-7543