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Assessing the effectiveness of whole blood–derived...
Journal article

Assessing the effectiveness of whole blood–derived platelets stored as a pool: a randomized block noninferiority trial

Abstract

BACKGROUND: Prestorage pooling of whole blood-derived platelets (PLTs) would simplify bacterial detection. This study evaluated the in vivo effect of the prestorage pooling of PLTs stored for up to 5 days, by assessing the corrected count increment (CCI) 18 to 24 hours after transfusion of the product. STUDY DESIGN AND METHODS: A randomized block noninferiority design was used. Eligible patients had chemotherapy-induced thrombocytopenia and …

Authors

Heddle NM; Cook RJ; Blajchman MA; Barty RL; Sigouin CS; Boye DM; Nelson EJ; Kelton JG

Journal

Transfusion, Vol. 45, No. 6, pp. 896–903

Publisher

Wiley

Publication Date

June 2005

DOI

10.1111/j.1537-2995.2005.04233.x

ISSN

0041-1132