An international investigation into O red blood cell unit administration in hospitals: the GRoup O Utilization Patterns (GROUP) study Academic Article uri icon

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abstract

  • BACKGROUND: Transfusion of group O blood to non-O recipients, or transfusion of D- blood to D+ recipients, can result in shortages of group O or D- blood, respectively. This study investigated RBC utilization patterns at hospitals around the world and explored the context and policies that guide ABO blood group and D type selection practices. STUDY DESIGN AND METHODS: This was a retrospective study on transfusion data from the 2013 calendar year. This study included a survey component that asked about hospital RBC selection and transfusion practices and a data collection component where participants submitted information on RBC unit disposition including blood group and D type of unit and recipient. Units administered to recipients of unknown ABO or D group were excluded. RESULTS: Thirty-eight hospitals in 11 countries responded to the survey, 30 of which provided specific RBC unit disposition data. Overall, 11.1% (21,235/191,397) of group O units were transfused to non-O recipients; 22.6% (8777/38,911) of group O D- RBC units were transfused to O D+ recipients, and 43.2% (16,800/38,911) of group O D- RBC units were transfused to recipients that were not group O D-. Disposition of units and hospital transfusion policy varied within and across hospitals of different sizes, with transfusion of group O D- units to non-group O D- patients ranging from 0% to 33%. CONCLUSION: A significant proportion of group O and D- RBC units were transfused to compatible, nonidentical recipients, although the frequency of this practice varied across sites.

authors

  • Zeller, Michelle
  • Barty, Rebecca
  • Aandahl, Astrid
  • Apelseth, Torunn O
  • Callum, Jeannie
  • Dunbar, Nancy M
  • Elahie, Allahna
  • Garritsen, Henk
  • Hancock, Helen
  • Kutner, José Mauro
  • Manukian, Belinda
  • Mizuta, Shuichi
  • Okuda, Makoto
  • Pagano, Monica B
  • Pogłód, Ryszard
  • Rushford, Kylie
  • Selleng, Kathleen
  • Sørensen, Claess Henning
  • Sprogøe, Ulrik
  • Staves, Julie
  • Weiland, Thorsten
  • Wendel, Silvano
  • Wood, Erica M
  • van de Watering, Leo
  • van Wordragen-Vlaswinkel, Maria
  • Ziman, Alyssa
  • Jan Zwaginga, Jaap
  • Murphy, Michael F
  • Heddle, Nancy
  • Yazer, Mark H

publication date

  • October 2017