Journal article
Urinary Biomarkers in Relapsing Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Abstract
OBJECTIVE: Glomerulonephritis (GN) is common in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), but tools for early detection of renal involvement are imperfect. We investigated 4 urinary proteins as markers of active renal AAV: alpha-1 acid glycoprotein (AGP), kidney injury molecule-1 (KIM-1), monocyte chemoattractant protein-1 (MCP-1), and neutrophil gelatinase-associated lipocalin (NGAL).
METHODS: Patients with active …
Authors
Lieberthal JG; Cuthbertson D; Carette S; Hoffman GS; Khalidi NA; Koening CL; Langford CA; Maksimowicz-McKinnon K; Seo P; Specks U
Journal
The Journal of Rheumatology, Vol. 40, No. 5, pp. 674–683
Publisher
The Journal of Rheumatology
Publication Date
May 2013
DOI
10.3899/jrheum.120879
ISSN
0315-162X
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
Acute-Phase ProteinsAdolescentAdultAgedAged, 80 and overAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisBiomarkersChemokine CCL2FemaleGlomerulonephritisHepatitis A Virus Cellular Receptor 1HumansLipocalin-2LipocalinsMaleMembrane GlycoproteinsMiddle AgedOrosomucoidPredictive Value of TestsProto-Oncogene ProteinsROC CurveReceptors, VirusRecurrenceTime FactorsYoung Adult