Free-breathing Pulmonary MR Imaging to Quantify Regional Ventilation.

Purpose To measure regional specific ventilation with free-breathing hydrogen 1 (¹H) magnetic resonance (MR) imaging without exogenous contrast material and to investigate correlations with hyperpolarized helium 3 (³He) MR imaging and pulmonary function test measurements in healthy volunteers and patients with asthma. Materials and Methods Subjects underwent free-breathing ¹H and static breath-hold hyperpolarized ³He MR imaging as well as …