Journal article
Gene expression analysis in asthma using a targeted multiplex array
Abstract
BackgroundGene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machinery and epithelial barrier integrity genes. We used a targeted gene expression arrays to identify changes in the expression and co-expression of genes important in asthma pathology.MethodsRNA was isolated from the airways of donor …
Authors
Pascoe CD; Obeidat M; Arsenault BA; Nie Y; Warner S; Stefanowicz D; Wadsworth SJ; Hirota JA; Jasemine Yang S; Dorscheid DR
Journal
BMC Pulmonary Medicine, Vol. 17, No. 1,
Publisher
Springer Nature
Publication Date
December 2017
DOI
10.1186/s12890-017-0545-9
ISSN
1471-2466