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Rivaroxaban with or without Aspirin in Stable...
Journal article

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease

Abstract

BACKGROUND: We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than aspirin alone for secondary cardiovascular prevention. METHODS: In this double-blind trial, we randomly assigned 27,395 participants with stable atherosclerotic vascular disease to receive rivaroxaban (2.5 mg twice daily) plus aspirin (100 mg once daily), rivaroxaban (5 mg twice daily), or aspirin (100 mg once daily). The primary …

Authors

Eikelboom JW; Connolly SJ; Bosch J; Dagenais GR; Hart RG; Shestakovska O; Diaz R; Alings M; Lonn EM; Anand SS

Journal

The New England Journal of Medicine, Vol. 377, No. 14, pp. 1319–1330

Publisher

Massachusetts Medical Society

Publication Date

October 5, 2017

DOI

10.1056/nejmoa1709118

ISSN

0028-4793