Journal article
Compensatory neutral mutations and the evolution of RNA
Abstract
There are many examples of RNA molecules in which the secondary structure has been strongly conserved during evolution, but the base sequence is much less conserved, e.g., transfer RNA, ribosomal RNA, and ribonuclease P. A model of compensatory neutral mutations is used here to describe the evolution of the base sequence in RNA helices. There are two loci (i.e., the two sides of the pair) with four alleles at each locus (corresponding to A, C, …
Authors
Higgs PG
Journal
Genetica, Vol. 102-103, No. 0, pp. 91–101
Publisher
Springer Nature
Publication Date
March 1998
DOI
10.1023/a:1017059530664
ISSN
0016-6707