Journal article
Functional Mapping of PilF and PilQ in the Pseudomonas aeruginosa Type IV Pilus System
Abstract
Pseudomonas aeruginosa uses type IV pili (T4P) to interact with the environment and as key virulence factors when acting as an opportunistic pathogen. Assembly of the outer membrane PilQ secretin channel through which the pili are extruded is essential for pilus biogenesis. The P. aeruginosa T4P pilotin, PilF, is required for PilQ outer membrane localization and assembly into secretins and contains six tetratricopeptide (TPR) protein-protein …
Authors
Koo J; Tang T; Harvey H; Tammam S; Sampaleanu L; Burrows LL; Howell PL
Journal
Biochemistry, Vol. 52, No. 17, pp. 2914–2923
Publisher
American Chemical Society (ACS)
Publication Date
April 30, 2013
DOI
10.1021/bi3015345
ISSN
0006-2960