Neural regulation of cholinesterase in newt skeletal muscle. III. Regulation in vitro by proteins from chick embryo brains

Abstract Triceps muscles of newts ( Notophthalmus viridescens ) lose AChE activity and show characteristic changes of various molecular forms of AChE after denervation in vivo or when maintained in organ culture (Rathbone et al., '79b). We examined the ability of nerve explants or homogenates from various sources to prevent the changes in total activity and molecular forms of AChE when added to the cultured muscles. These included dorsal root …