selected scholarly activity
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conferences
- Exposure in vivo of rabbit platelets to thrombospheres augments the ADP-induced decrease in platelet phosphatidylinositol 4,5-bisphosphate (PIP2) ex vivo.. Blood. 2998-2998. 1997
- Binding of thrombospheres to chymotrypsin-treated rabbit platelets decreases phosphatidylinositol 4,5-bisphosphate (PIP2). Thrombosis and Haemostasis. P1964-P1964. 1997
- Protein phosphatase inhibitors inhibit signalling between binding of polymerizing fibrin to chymotrypsin-treated (CT) rabbit platelets and enzymes of phospho-inositide interconversion. Thrombosis and Haemostasis. P1079-P1079. 1997
- Changes in polyphosphoinositides in chymotrypsin-treated rabbit platelets are closely linked to binding of polymerizing fibrin to glycoprotein IIb/IIIa.. The FASEB Journal. 2396-2396. 1996
- MCNUTRITION - A COMPUTER-BASED SELF-DIRECTED LEARNING-RESOURCE ON NUTRITION FOR MEDICAL AND HEALTH-SCIENCE STUDENTS. American Journal of Clinical Nutrition. 907-907. 1995
- DIFFERENCES IN THROMBIN-STIMULATES AND SFLLRN-STIMULATED PHOSPHOINOSITIDE METABOLISM IN HUMAN PLATELETS. The FASEB Journal. A59-A59. 1995
- POLYMERIZING FIBRIN DECREASES PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE (PIP(2)) IN CHYMOTRYPSIN-TREATED RABBIT PLATELETS. Thrombosis and Haemostasis. 1341-1341. 1993
- ROLE OF FIBRINOGEN BINDING TO PLATELETS IN ADP-STIMULATED POLYPHOSPHOINOSITIDE METABOLISM OF HUMAN PLATELETS. Thrombosis and Haemostasis. 1001-1001. 1993
- CHANGES IN PHOSPHOINOSITIDES IN RABBIT PLATELETS STIMULATED BY PLATELET-ACTIVATING-FACTOR (PAF) IN THE PRESENCE OF POLYMERIZING FIBRIN. The FASEB Journal. A1313-A1313. 1992
- EPA INHIBITS INOSITOL PHOSPHATE FORMATION IN U46619-STIMULATED RABBIT PLATELETS. The FASEB Journal. A1163-A1163. 1988
- EFFECT OF EXTERNAL CA-2+ ON ADP-INDUCED PHOSPHOLIPID CHANGES IN HUMAN-PLATELETS. The FASEB Journal. A398-A398. 1988
- PLATELET-FIBRIN CLOTS FORMED BY THROMBIN SELECTIVELY RETAIN PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE (PIP2). Thrombosis and Haemostasis. 275-275. 1987
- ENHANCED THROMBIN-INDUCED AGGREGATION AND INOSITOL TRISPHOSPHATE FORMATION OF PLATELETS FROM SPONTANEOUSLY HYPERCHOLESTEROLEMIC RATS. Thrombosis and Haemostasis. 276-276. 1987
- ETHANOL INHIBITS THROMBIN-INDUCED INOSITOL TRISPHOSPHATE PRODUCTION BY RABBIT PLATELETS. Circulation. 97-97. 1986
- Effects of epinephrine on ADP-induced changes in platelet inositol phosphates. The FASEB Journal. 229-229. 1986
- MEPACRINE INHIBITS THE DEGRADATION OF PHOSPHATIDYLINOSITOL BUT NOT OF THE POLYPHOSPHOINOSITIDES IN THROMBIN-STIMULATED, WASHED RABBIT PLATELETS. The FASEB Journal. 1663-1663. 1985
- STIMULATION OF THE PLATELET-RELEASE REACTION BY THE IONOPHORE A23187 INVOLVES INOSITOL TRISPHOSPHATE (IP3). Thrombosis and Haemostasis. 113-113. 1985
- THE EFFECT OF EPINEPHRINE ON ADP-INDUCED CHANGES IN RABBIT PLATELET PHOSPHOINOSITIDE METABOLISM. Thrombosis and Haemostasis. 14-14. 1985
- THROMBIN AND ADP DECREASE PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE IN WASHED RABBIT PLATELETS BY DIFFERENT MECHANISMS. Circulation. 49-49. 1984
- THROMBIN-INDUCED INCREASE IN INOSITOL PHOSPHATES DURING AGGREGATION AND RELEASE FROM WASHED RABBIT PLATELETS. The FASEB Journal. 979-979. 1984
- ADP-INDUCED CHANGES IN PHOSPHOLIPIDS OF RABBIT AND HUMAN-PLATELETS. Thrombosis and Haemostasis. 363-363. 1983
- EFFECT OF ARTERIAL INJURY ON LIPID-METABOLISM IN ENDOTHELIUM COVERED NEO-INTIMA. The FASEB Journal. 792-792. 1983
- THROMBIN STIMULATION OF WASHED RABBIT PLATELETS CAUSES AN EARLY INCREASE IN PHOSPHATIDYLINOSITOL. The FASEB Journal. 659-659. 1983
- RABBIT PLATELET PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE (PIP2) IS PRESENT IN MORE THAN ONE POOL. The FASEB Journal. 701-701. 1982
- Changes In Triphosphatidylinositol Metabolism During PGE1- Induced Shape Change Of Washed Rabbit Platelets. Thrombosis and Haemostasis. 295-295. 1981
- THE EFFECT OF PHENYTOIN ON MEMBRANE-PROTEIN PHOSPHORYLATION IN PATIENTS WITH MYOTONIC MUSCULAR-DYSTROPHY. Canadian Journal of Neurological Sciences. 125-125. 1980
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journal articles
- Binding of polymerizing fibrin to integrin alpha IIb beta3 on chymotrypsin-treated rabbit platelets decreases phosphatidylinositol 4,5-bisphosphate and increases cytoskeletal actin. Platelets. 10:228-237. 1999
- In contrast to fibrinogen or fibrin, peptide and peptide mimetic binding to alpha does not cause outside-in signalling as judged by measurements of phosphatidylinositol 4,5-bisphosphate beta (GPIIb-IIIa) IIb 3. Platelets. 9:390-394. 1998
- Strategies for diagnosing and managing medication-induced headache.. Canadian Family Physician. 43:1249-1254. 1997
- Differences between platelet phosphoinositide metabolism stimulated by thrombin or SFLLRN are not accounted for by interaction of thrombin with glycoprotein Ib. American Journal of Hematology. 54:288-295. 1997
- Extraction of Polyphosphoinositides from Platelets: Comparison of a Two-Step Procedure with a Common Single-Step Extraction Procedure. Analytical Biochemistry. 224:449-451. 1995
- Polymerizing Fibrin Decreases the Polyphosphoinositides in Chymotrypsin‐Treated Human Platelets. Annals of the New York Academy of Sciences. 714:287-290. 1994
- U73122 affects the equilibria between the phosphoinositides as well as phospholipase C activity in unstimulated and thrombin-stimulated human and rabbit platelets.. Journal of Pharmacology and Experimental Therapeutics. 266:1156-1163. 1993
- ADP‐stimulated fibrinogen binding is necessary for some of the inositol phospholipid changes found in ADP‐stimulated platelets. The FEBS Journal. 216:231-237. 1993
- A Significant Portion of the Aequorin Luminescent Signal from Stimulated Human and Rabbit Platelets is Due to Exposure of the Aequorin to Calcium in the Suspending Medium. Thrombosis and Haemostasis. 70:807-811. 1993
- Polyphosphoinositide Changes in Rabbit Platelets Stimulated with Platelet Activating Factor During the Formation of Platelet-fibrin Clots. Platelets. 3:201-209. 1992
- The inadequacy of recent research on computer-assisted instruction. Academic Medicine. 66:444-8. 1991
- Inositol phospholipid metabolism in human platelets stimulated by ADP. The FEBS Journal. 193:521-528. 1990
- Catching information technology by the tail for problem‐based learning. Journal of Dental Education. 54:557-559. 1990
- Thrombin-induced inositol phosphate production by platelets from rats with diet-induced or genetically determined hypercholesterolemia.. Translational Research. 115:241-248. 1990
- Changes in Phosphoinositides in Rabbit Platelets during Clot Formation. Comparison of Platelets Stimulated by ADP or by Thrombin in the Presence of Polymerising Fibrin. Platelets. 1:199-204. 1990
- Eicosapentaenoic Acid Interferes with U46619-Stimulated Formation of Inositol Phosphates in Washed Rabbit Platelets. Thrombosis and Haemostasis. 62:1116-1120. 1989
- Thrombin-induced inositol trisphosphate production by rabbit platelets is inhibited by ethanol. Biochemical Journal. 251:279-284. 1988
- Phosphatidylinositol 4,5-bisphosphate is selectively retained by platelet-fibrin clots formed by thrombin. Biochemical Journal. 245:649-653. 1987
- Involvement of phosphoinositide metabolism in potentiation by adrenaline of ADP-induced aggregation of rabbit platelets. Biochemical Journal. 242:841-847. 1987
- The phosphoinositides exist in multiple metabolic pools in rabbit platelets. Biochemical Journal. 238:411-417. 1986
- The decrease in phosphatidylinositol 4,5-bisphosphate in ADP-stimulated washed rabbit platelets is not primarily due to phospholipase C activation. Biochemical Journal. 237:327-332. 1986
- Development of synaptic currents in immobilized muscle of Xenopus laevis.. Journal of Physiology. 364:57-68. 1985
- Accumulation of the inositol phosphates in thrombin-stimulated, washed rabbit platelets in the presence of lithium. Biochemical Journal. 224:399-405. 1984
- Changes in the platelet phosphoinositides during the first minute after stimulation of washed rabbit platelets with thrombin. Biochemical Journal. 219:25-31. 1984
- ADP-Induced changes in [32P]phosphate labeling of phosphatidylinositol-4,5-bisphosphate in washed rabbit platelets made refractory by prior ADP stimulation. Biochemical and Biophysical Research Communications. 113:483-490. 1983
- Changes in phosphatidylinositol-4,5-bisphosphate 10 seconds after stimulation of washed rabbit platelets with ADP. Blood. 60:1247-1250. 1982
- The effect of prostaglandins E1, I2 and F2α on the shape and phosphatidylinositol-4,5-bisphosphate metabolism of washed rabbit platelets. Thrombosis Research. 28:731-740. 1982
- The inhibitory effects of exogenous arachidonic acid on rabbit platelet aggregation and the release reaction. Blood. 60:1179-1187. 1982
- Neural regulation of cholinesterase in newt skeletal muscle. I. Distribution and characterization of the enzyme species. Journal of Experimental Zoology. 210:435-450. 1979
- Neural regulation of cholinesterase in newt skeletal muscle. II. The effects of denervation and of culture in vitro. Journal of Experimental Zoology. 210:451-462. 1979
- Neural regulation of cholinesterase in newt skeletal muscle. III. Regulation in vitro by proteins from chick embryo brains. Journal of Experimental Zoology. 210:463-472. 1979
- The effect of membrane cholesterol depletion upon erythrocyte membrane-bound enzymes. Biochemistry and Cell Biology. 57:1144-1152. 1979
- Myotonic muscular dystrophy. Neurology. 29:791-791. 1979
- Phosphorylation of casein by human erythrocyte membrane-bound protein kinase: competition of casein with endogenous substrates. Journal of Membrane Biology. 49:123-138. 1979
- Alterations of erythrocyte ghost protein phosphorylation in the duchenne and myotonic muscular dystrophies. Molecular Genetics and Metabolism. 20:434-439. 1978
- Alterations of Membrane Phosphorylation in Erythrocyte Membranes from Patients with Duchenne Muscular Dystrophy. Canadian Journal of Neurological Sciences. 5:437-442. 1978
- Red-Cell Stability in Duchenne's Syndrome. New England Journal of Medicine. 298:403-403. 1978
- Alterations in erythrocyte membrane material properties: a marker of the membrane abnormality in human and chicken muscular dystrophy.. Progress in Clinical and Biological Research. 20:189-203. 1978
- Elevated cholesterol in tissues of chicken embryos with hereditary myotonic muscular dystrophy. Experimental Neurology. 57:475-485. 1977