Journal article
Characterization of Fluorescence Lifetime of Photofrin and Delta-Aminolevulinic Acid Induced Protoporphyrin IX in Living Cells using Single- and Two-Photon Excitation
Abstract
Photodynamic therapy (PDT) is an effective treatment option for various types of invasive tumors. The efficacy of PDT treatment depends strongly on selective cell uptake and selective excitation of the tumor. The characterization of fluorescence lifetimes of photosensitizers localized inside living cells may provide the basis for further investigation of in vivo PDT dosage measurements using time-domain spectroscopy and imaging. In this …
Authors
Russell JA; Diamond KR; Collins TJ; Tiedje HF; Hayward JE; Farrell TJ; Patterson MS; Fang Q
Journal
IEEE Journal of Selected Topics in Quantum Electronics, Vol. 14, No. 1, pp. 158–166
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Publication Date
January 1, 2008
DOI
10.1109/jstqe.2007.912896
ISSN
0792-1233