Journal article
Effects of intensive glycaemic control on ischaemic heart disease: analysis of data from the randomised, controlled ACCORD trial
Abstract
BACKGROUND: Hyperglycaemia could substantially increase the risk of ischaemic heart disease in patients with type 2 diabetes. We investigated whether intensive lowering of glucose concentrations affects risk.
METHODS: We assessed 10,251 adults aged 40-79 years with established type 2 diabetes, mean glycated haemoglobin A1c (HbA1c) concentration of 67 mmol/mol (8·3%), and risk factors for ischaemic heart disease enrolled in the ACCORD trial. …
Authors
Gerstein HC; Miller ME; Ismail-Beigi F; Largay J; McDonald C; Lochnan HA; Booth GL; Group FTAS
Journal
The Lancet, Vol. 384, No. 9958, pp. 1936–1941
Publisher
Elsevier
Publication Date
November 2014
DOI
10.1016/s0140-6736(14)60611-5
ISSN
0140-6736