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Stromally Expressed β-Catenin Modulates Wnt9b...
Journal article

Stromally Expressed β-Catenin Modulates Wnt9b Signaling in the Ureteric Epithelium

Abstract

The mammalian kidney undergoes cell interactions between the epithelium and mesenchyme to form the essential filtration unit of the kidney, termed the nephron. A third cell type, the kidney stroma, is a population of fibroblasts located in the kidney capsule, cortex and medulla and is ideally located to affect kidney formation. We found β-catenin, a transcriptional co-activator, is strongly expressed in distinctive intracellular patterns in the …

Authors

Boivin FJ; Sarin S; Lim J; Javidan A; Svajger B; Khalili H; Bridgewater D

Journal

PLOS ONE, Vol. 10, No. 3,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0120347

ISSN

1932-6203