Journal article
There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum
Abstract
Proteins of the Bcl-2 family are important regulators of cell fate. The role of these proteins in controlling mitochondrial apoptotic processes has been extensively investigated, although exact molecular mechanisms are incompletely understood. However, mounting evidence indicates that these proteins also function at the endoplasmic reticulum and other locations within the cell. Both pro- and anti-apoptotic Bcl-2 family members can regulate …
Authors
Annis MG; Yethon JA; Leber B; Andrews DW
Journal
Biochimica et Biophysica Acta, Vol. 1644, No. 2-3, pp. 115–123
Publisher
Elsevier
Publication Date
March 2004
DOI
10.1016/j.bbamcr.2003.07.001
ISSN
0006-3002