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Impact of denosumab on the peripheral skeleton of...
Journal article

Impact of denosumab on the peripheral skeleton of postmenopausal women with osteoporosis

Abstract

OBJECTIVE: The aim of this study was to report the effects of denosumab on radius cortical and trabecular bone density, mass, and strength, and wrist fracture incidence in the FREEDOM (Fracture REduction Evaluation of Denosumab in Osteoporosis every 6 Months) study. METHODS: In the FREEDOM study, postmenopausal women with osteoporosis (N = 7,808) received placebo or 60 mg of denosumab every 6 months for 36 months. Radius bone mineral density …

Authors

Simon JA; Recknor C; Moffett AH; Adachi JD; Franek E; Lewiecki EM; McClung MR; Mautalen CA; Ragi-Eis S; Nicholson GC

Journal

Menopause The Journal of The North American Menopause Society, Vol. 20, No. 2, pp. 130–137

Publisher

Wolters Kluwer

Publication Date

2 2013

DOI

10.1097/gme.0b013e318267f909

ISSN

1072-3714