Journal article
Cytokine modulation of T-lymphocyte activation by intestinal smooth muscle cells
Abstract
BACKGROUND & AIMS: Interleukin 1beta (IL-beta) and tumor necrosis factor alpha (TNF-alpha) are present in the neuromuscular layers during intestinal inflammation and directly affect intestinal smooth muscle function. We investigated whether IL-1beta and TNF-alpha modulate T-cell activation by murine intestinal smooth muscle cells (ISMCs).
METHODS: alpha- and gamma- actin expression in ISMCs was confirmed using reverse-transcription polymerase …
Authors
Hogaboam C; Snider D; Collins S
Journal
Gastroenterology, Vol. 112, No. 6, pp. 1986–1995
Publisher
Elsevier
Publication Date
June 1997
DOI
10.1053/gast.1997.v112.pm9178691
ISSN
0016-5085