Journal article
Accuracy of immunoglobulin M immunoassay for diagnosis of chlamydial infections in infants and adults
Abstract
An improved solid-phase enzyme immunoassay (EIA) with Chlamydia trachomatis L2 434/Bu elementary bodies was developed for the measurement of immunoglobulin M (IgM) antibody to C. trachomatis in serum. Comparison of EIA and microimmunofluorescence IgM antibody titers of 156 serum samples revealed an EIA sensitivity and specificity of 100% for infants, but reduced sensitivity (85%) and specificity (76%) for sera from adults. Sera containing IgM …
Authors
Mahony JB; Chernesky MA; Bromberg K; Schachter J
Journal
Journal of Clinical Microbiology, Vol. 24, No. 5, pp. 731–735
Publisher
American Society for Microbiology
Publication Date
11 1986
DOI
10.1128/jcm.24.5.731-735.1986
ISSN
0095-1137