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Cross-resistance to photofrin-mediated...
Journal article

Cross-resistance to photofrin-mediated photodynamic therapy and UV light and recovery from photodynamic therapy damage in Rif-8A mouse fibrosarcoma cells measured using viral capacity

Abstract

Photodynamic therapy (PDT) utilizes the localized delivery of light to activate a photosensitizing drug (such as Photofrin) which is selectively retained by the tumour tissues. The intrinsic in vitro sensitivity of tumour cells to PDT is thought to be an important determinant of clinical tumour response to PDT. In this work we show the feasibility of using a viral capacity assay for adenovirus (Ad) DNA synthesis as an indicator of cellular …

Authors

DiProspero L; Singh G; Wilson BC; Rainbow AJ

Journal

Journal of Photochemistry and Photobiology B Biology, Vol. 38, No. 2-3, pp. 143–151

Publisher

Elsevier

Publication Date

April 1997

DOI

10.1016/s1011-1344(96)07462-3

ISSN

1011-1344