Journal article
Transient Expression of Na+/H+ Exchanger Isoform NHE-2 in LLC-PK1 Cells: Inhibition of Endogenous NHE-3 and Regulation by Hypertonicity
Abstract
Abstract. Na+/H+ exchanger isoforms NHE-2 and NHE-3 demonstrate distinct tissue expression patterns in renal epithelial cells. NHE-2 is predominantly expressed in the inner medulla whereas NHE-3 is highly expressed in the proximal tubule cells. The purpose of the current experiments was to study the characteristics of NHE-2 upon its own expression in cultured proximal tubule cells, LLC-PK1. Toward this end, LLC-PK1 cells were subjected to six …
Authors
Singh G; Orlowski J; Soleimani M
Journal
The Journal of Membrane Biology, Vol. 151, No. 3, pp. 261–268
Publisher
Springer Nature
Publication Date
June 1996
DOI
10.1007/s002329900076
ISSN
0022-2631