Journal article
The interaction of metal ions with synthetic DNA: Induction of conformational and structural transitions
Abstract
The propensity of a large number of metal ions to induce cooperative conformational or structural transitions in double-stranded poly d(G-C) was assessed by UV and CD spectrometry. This ability was seen to be an intrinsic property of most metal ions. The observed (metal ion)/(polydeoxynucleotide) mole ratio calculated per G-C base pair and corresponding to the midpoints of the principal transition ranged from 0.3 (Ag(II) to 100 (Al(III)). A …
Authors
Rossetto FE; Nieboer E
Journal
Journal of Inorganic Biochemistry, Vol. 54, No. 3, pp. 167–186
Publisher
Elsevier
Publication Date
May 1994
DOI
10.1016/0162-0134(94)80011-1
ISSN
0162-0134