Journal article
Random segregation of multiple genetic markers from CHO-CHO hybrids: Evidence for random distribution of functional hemizygosity in the genome
Abstract
The linkage relationship between various recessive markers isolated in Chinese hamster ovary (CHO) cells has been investigated. For such studies, multiple recessive markers conferring resistance to various drugs, e.g., resistance to emetine (Emtr), thioguanine (Thgr), azaadenine (Azar), phytohemagglutinin (Phar), diphtheria toxin (Dipr), toyocamycin Toyr), aminopterin (Amnr), and methylglyoxalbisguanyl hydrazone (Mbgr), were introduced into CHO …
Authors
Gupta RS
Journal
Somatic Cell Genetics, Vol. 6, No. 1, pp. 115–125
Publisher
Springer Nature
Publication Date
January 1980
DOI
10.1007/bf01538700
ISSN
0098-0366