Journal article
Vinblastine‐Induced Erythrocytotoxicity
Abstract
At a therapeutic concentration (10 −6 mol/l), vinblastine causes no significant changes of erythrocyte morphology in whole blood in vitro, but, with 30% red cell suspensions in buffer, the drug is stomatocytogenic. Several pathogenetic mechanisms are considered and the clinical relevance of this finding is assessed.
Authors
Neville AJ; Rand CA; Barr RD
Journal
European Journal Of Haematology, Vol. 28, No. 1, pp. 32–38
Publisher
Wiley
Publication Date
January 1982
DOI
10.1111/j.1600-0609.1982.tb02117.x
ISSN
0902-4441