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Ca2+ channel ligand activities in uterine smooth...
Journal article

Ca2+ channel ligand activities in uterine smooth muscle: influence of hormonal status

Abstract

The effects of estrogen and progesterone domination, achieved by administering estrogen (E) and estrogen plus progesterone (E + P), on rat uterine reactivity to Ca2+ and to Ca2+ channel ligands (antagonist and activator) were compared. The inhibitory activities of nifedipine, diltiazem, and D 600 against K+ depolarization-induced responses were not significantly different between E- and E + P-dominated states in longitudinal or circular muscle …

Authors

Ruzycky AL; Crankshaw DJ; Triggle DJ

Journal

Canadian Journal of Physiology and Pharmacology, Vol. 65, No. 10, pp. 2085–2092

Publisher

Canadian Science Publishing

Publication Date

October 1, 1987

DOI

10.1139/y87-327

ISSN

0008-4212