Journal article
The direct binding of human factor VII in plasma to recombinant human tissue factor
Abstract
The extrinsic pathway of coagulation is initiated when zymogen factor VII binds to its cell surface receptor tissue factor. Recently recombinant human tissue factor has become available and therefore in this study the direct binding of human factor VII in plasma to recombinant tissue factor was explored. Factor VII binding was quantitated by a standard ELISA protocol using monospecific polyclonal rabbit anti-human factor VII as the primary …
Authors
Sridhara S; Clarke BJ; Ofosu FA; High KA; Blajchman MA
Journal
Thrombosis Research, Vol. 70, No. 4, pp. 307–316
Publisher
Elsevier
Publication Date
May 1993
DOI
10.1016/0049-3848(93)90103-u
ISSN
0049-3848