Journal article
Probable regulation of factor VIIa–tissue factor and prothrombinase by factor Xa–TFPI and TFPI in vivo
Abstract
Given that factor VIIa-tissue factor (TF) probably initiates coagulation in vivo, this study investigated the relationship between plasma concentrations of factor VIIa and prothrombin fragment 1 + 2 in plasma (the latter as an index of prothrombinase activity in vivo). The relationships between these two parameters and the concentrations of tissue factor pathway inhibitor (TFPI) and factor Xa-TFPI in plasma were also investigated. TFPI …
Authors
Gouin‐Thibault I; Dewar L; Craven S; Kulczycky M; Wun T; Ofosu FA
Journal
British Journal of Haematology, Vol. 95, No. 4, pp. 738–746
Publisher
Wiley
Publication Date
December 1996
DOI
10.1046/j.1365-2141.1996.d01-1963.x
ISSN
0007-1048