Journal article
Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo
Abstract
The serum levels of interleukin 6 (IL-6) and the expression (mRNA) of the 80 kDa IL-6 receptor (IL-6R) were examined in three different models of acute inflammation. Rats were treated with either Freund's complete adjuvant (FA) via intraperitoneal injection, LPS via intravenous injection, or turpentine via subcutaneous injection. Using bio- and specific immunoassays, rat serum levels of IL-6, corticosterone, and acute phase proteins were …
Authors
Geisterfer M; Richards C; Baumann M; Fey G; Gywnne D; Gauldie J
Journal
Cytokine, Vol. 5, No. 1, pp. 1–7
Publisher
Elsevier
Publication Date
January 1993
DOI
10.1016/1043-4666(93)90017-y
ISSN
1043-4666