Journal article
Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis
Abstract
The currently accepted approach to treatment of idiopathic pulmonary fibrosis (IPF) is based on the assumption that it is a chronic inflammatory disease, and most available antiinflammatory drugs target numerous biological processes involving multiple genes, but are not often beneficial. More novel therapeutic strategies take recent findings about the underlying molecular mechanisms of fibrogenesis into account, and ongoing and as yet …
Authors
Ask K; Martin GEM; Kolb M; Gauldie J
Journal
Annals of the American Thoracic Society, Vol. 3, No. 4, pp. 389–393
Publisher
American Thoracic Society
Publication Date
June 1, 2006
DOI
10.1513/pats.200602-021tk
ISSN
2329-6933
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Clinical Trials as TopicConnective Tissue Growth FactorEtanerceptExtracellular MatrixHumansImmediate-Early ProteinsImmunoglobulin GIntercellular Signaling Peptides and ProteinsPlatelet-Derived Growth FactorPulmonary FibrosisReceptors, Tumor Necrosis FactorSignal TransductionSmad3 ProteinTransforming Growth Factor betaTumor Necrosis Factor-alpha