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Efficacy and Safety of Fixed Low-Dose Dalteparin...
Journal article

Efficacy and Safety of Fixed Low-Dose Dalteparin in Preventing Venous Thromboembolism Among Obese or Elderly Hospitalized Patients: A Subgroup Analysis of the PREVENT Trial

Abstract

BACKGROUND: We were concerned that a fixed rather than a weight-based dosing regimen of dalteparin sodium to prevent venous thromboembolism (VTE) might result in decreased efficacy in obese patients and decreased safety in elderly patients. METHODS: We retrospectively performed subgroup analyses using the database from the Prospective Evaluation of Dalteparin Efficacy for Prevention of VTE in Immobilized Patients (PREVENT) Trial, a study of …

Authors

Kucher N; Leizorovicz A; Vaitkus PT; Cohen AT; Turpie AGG; Olsson C-G; Goldhaber SZ

Journal

JAMA Internal Medicine, Vol. 165, No. 3, pp. 341–345

Publisher

American Medical Association (AMA)

Publication Date

February 14, 2005

DOI

10.1001/archinte.165.3.341

ISSN

2168-6106