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Ion Transport in Rat Tracheal Epithelium In Vitro:...
Journal article

Ion Transport in Rat Tracheal Epithelium In Vitro: Role of Capsaicin-sensitive Nerves in Allergic Reactions

Abstract

Tracheas from control rats or rats sensitized to egg albumin (EA) were studied in vitro in Ussing chambers, and changes in short-circuit current (Isc) induced by the addition of antigen or agonists on the mucosal (luminal) side were recorded. Addition of EA (100 micrograms/ml) to tracheas from sensitized but not from control rats caused a slow increase of Isc beginning after 15 to 30 s and maximal at 3 to 4 min. This response was inhibited in …

Authors

Sestini P; Bienenstock J; Crowe SE; Marshall JS; Stead RH; Kakuta Y; Perdue MH

Journal

American Journal of Respiratory and Critical Care Medicine, Vol. 141, No. 2, pp. 393–397

Publisher

American Thoracic Society

Publication Date

February 1990

DOI

10.1164/ajrccm/141.2.393

ISSN

1073-449X