Journal article
Altered Guanosine and Guanine Concentrations in Rabbit Striatum Following Increased Dopamine Turnover
Abstract
The significance of guanine nucleotides and nucleosides in neurodegenerative disorders is suggested by recent reports that these molecules enhance neurite branching and astrocyte proliferation. The objective of this study was to investigate the influence of increased dopamine metabolism, produced by 5-day treatment of rabbits with reserpine (2 mg/kg) or levodopa (LD) (50 mg/kg), on striatal concentrations of guanosine, guanine, and their …
Authors
Loeffler DA; LeWitt PA; Juneau PL; Camp DM; DeMaggio AJ; Milbury P; Matson WR; Rathbone MP
Journal
Brain Research Bulletin, Vol. 45, No. 3, pp. 297–299
Publisher
Elsevier
Publication Date
February 1998
DOI
10.1016/s0361-9230(97)00367-5
ISSN
0361-9230