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Comparative catabolism of prothrombin and...
Journal article

Comparative catabolism of prothrombin and antithrombin in normal and alloxan-diabetic rabbits

Abstract

Previous studies have shown that alloxan-induced diabetes in rabbits effects a slower release of plasma proteins from the liver, a slower synthesis of 35S-glycosaminoglycan in the extracellular matrix of the arterial wall, and a concurrent reduction in the fractional catabolic rates of several plasma proteins. In the present study, the catabolism of two hemostatic proteins, prothrombin and antithrombin, are compared in alloxan-induced diabetic …

Authors

Hatton MWC; Southward SMR; Blajchman MA; Ross B; Winocour PD; Richardson M

Journal

Metabolism, Vol. 46, No. 12, pp. 1406–1411

Publisher

Elsevier

Publication Date

December 1997

DOI

10.1016/s0026-0495(97)90139-6

ISSN

0026-0495