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CD11c/CD18 on neutrophils recognizes a domain at...
Journal article

CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen.

Abstract

Fibrinogen and fibrin serve as adhesive substrates for a variety of cells including platelets, endothelial cells, and leukocytes. Previously, we identified the C terminus of the gamma chain of fibrinogen as the region of the fibrinogen molecule that contains a ligand for CD11b/CD18 (complement receptor 3) on phorbol ester-stimulated polymorphonuclear leukocytes. In contrast, we report here that neutrophils stimulated with tumor necrosis factor …

Authors

Loike JD; Sodeik B; Cao L; Leucona S; Weitz JI; Detmers PA; Wright SD; Silverstein SC

Journal

Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, No. 3, pp. 1044–1048

Publisher

Proceedings of the National Academy of Sciences

Publication Date

2 1991

DOI

10.1073/pnas.88.3.1044

ISSN

0027-8424