Journal article
The effect of intra-gastric acidity and flora on the concentration of N-nitroso compounds in the stomach
Abstract
BACKGROUND: Correa's hypothesis proposes that gastric carcinogenesis is due to atrophic gastritis and hypochlorhydria which permit gastric bacterial colonization, the reduction of dietary nitrates to nitrites and the formation of potentially carcinogenic N-nitroso compounds (NOCs).
OBJECTIVE: To test the hypothesis that omeprazole-induced hypochlorhydria is associated with increased intra-gastric concentrations of nitrate-reducing bacteria …
Authors
Viani F; Siegrist HH; Pignatelli B; Cederberg C; Idström JP; Verdu EF; Fried M; Blum AL; Armstrong D
Journal
European Journal of Gastroenterology & Hepatology, Vol. 12, No. 2, pp. 165–173
Publisher
Wolters Kluwer
Publication Date
February 2000
DOI
10.1097/00042737-200012020-00006
ISSN
0954-691X