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The effect of elastomer chain flexibility on...
Journal article

The effect of elastomer chain flexibility on protein adsorption

Abstract

Cells are known to respond differently when grown on materials of varying stiffness. However, the mechanism by which a cell senses substrate stiffness is unknown. Lower crosslink density elastomers formed from acrylated star-poly(d,l lactide-co-ϵ-caprolactone) have previously been shown to support higher smooth muscle cell proliferation in in vitro culture. This difference in growth was hypothesized to be due to differences in protein …

Authors

Vyner MC; Liu L; Sheardown HD; Amsden BG

Journal

Biomaterials, Vol. 34, No. 37, pp. 9287–9294

Publisher

Elsevier

Publication Date

December 2013

DOI

10.1016/j.biomaterials.2013.08.086

ISSN

0142-9612