Journal article
Imipramine reverses alterations in cytokines and BDNF levels induced by maternal deprivation in adult rats
Abstract
A growing body of evidence is pointing toward an association between immune molecules, as well brain-derived neurotrophic factor (BDNF) and the depression. The present study was aimed to evaluate the behavioral and molecular effects of the antidepressant imipramine in maternally deprived adult rats. To this aim, maternally deprived and non-deprived (control group) male rats were treated with imipramine (30mg/kg) once a day for 14 days during …
Authors
Réus GZ; dos Santos MAB; Abelaira HM; Ribeiro KF; Petronilho F; Vuolo F; Colpo GD; Pfaffenseller B; Kapczinski F; Dal-Pizzol F
Journal
Behavioural Brain Research, Vol. 242, , pp. 40–46
Publisher
Elsevier
Publication Date
April 2013
DOI
10.1016/j.bbr.2012.11.044
ISSN
0166-4328